Publications of Alex Binder

2013

Couto-Alves A, Wright VJ, Perumal K, Binder A, Carrol ED, Emonts M, de Groot R, Hazelzet J, Kuijpers T, Nadel S, Zenz W, Ramnarayan P, Levin M, Coin L, Inwald DP. A new scoring system derived from base excess and platelet count at presentation predicts mortality in paediatric meningococcal sepsis. Crit Care 17(2):R68-R68, 2013

2012

Binder A, Martinon-Torres F, Levin M, Hibberd ML, Zenz W. A genome-wide association study of meningococcal disease identifies novel susceptibility and severity genes in a paediatric meningococcal patient cohort. Eur J Pediat 171(9):1426-1426, 2012

2010

Davila S, Wright VJ, Khor CC, Sim KS, Binder A, Breunis WB, Inwald D, Nadel S, Betts H, Carrol ED, de Groot, R, Hermans PW, Hazelzet J, Emonts M, Lim CC, Kuijpers TW, Martinon-Torres F, Salas A, Zenz W, Levin M, Hibberd ML. Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. Nature Genetics 42(9):772-776, 2010

2009

Resch B, Radinger A, Mannhalter C, Binder A, Haas J, Müller WD. Interleukin-6 G(--174)C polymorphism is associated with mental retardation in cystic periventricular leucomalacia in preterm infants. Arch Dis Child Fetal Neonatal 94(4):F304-F306, 2009

Binder A, Müller M, Resch B, Mannhalter C, Zenz W. Combined haplotypes of protein C and endothelial protein C receptor Association with outcome, purpura fulminans, and susceptibility in children with meningococcaemia. Hämostaseologie 29:S108-S109, 2009

2007

Binder A, Endler G, Müller M, Mannhalter C, Zenz W. 4G4G genotype of the plasminogen activator inhibitor-1 promoter polymorphism associates with disseminated intravascular coagulation in children with systemic meningococcemia. Journal of Thrombosis and Haemostasis 5(10):2049-54, 2007 [PDF]

Binder A, Endler G, Rieger S, Geishofer G, Resch B, Mannhalter C, Zenz W. Protein C promoter polymorphisms associate with sepsis in children with
systemic meningococcemia. Human Genetics 122(2):183-90, 2007 [PDF]

Binder A. A review of the genetics of essential hypertension. Current Opinion Cardiology 22(3):176-84, 2007 (Abstract)

2006

Binder A. Identification of genes for a complex trait: Examples from hypertension (Review). Current Pharmaceutical Biotechnology 7(1):1-13, 2006 (Abstract)

Endler G, Marculescu R, Binder A, Geishofer G, Müller MR, Zöhrer B, Resch B, Müller W, Zenz W, Mannhalter C. Polymorphisms in the Interleukin 1 Gene Cluster in Children with Systemic Meningococcaemia. Clinical Chemistry 52(3):511-14, 2006

Binder A, Garcia E, Wallace C, Kazeem G, Ben-Shlomo Y, Sweetnam P, Caulfield M, Skrabal F, Kotanko P, Munroe P. Haplotypes of the beta-2 adrenergic receptor associate with high diastolic blood pressure in the Caerphilly Prospective Study. J of Hypertension 24(3):471-477, 2006 [PDF]

2005

Geishofer G, Binder A, Müller MR, Zöhrer B, Resch B, Müller W, Faber J, Finn A, Endler G, Mannhalter C, Zenz W. 4G/5G Promoter Polymorphism in the Plasminogen- Activator-Inhibitor-1 Gene in Children with Systemic Meningo-coccaemia. European Journal of Pediatrics 164:486-490, 2005 [PDF]

Binder A, Müller W, Endler G, Mannhalter C, Zenz W. 4G/4G Allele of the plasminogen activator inhibitor-1 gene is associated with thrombocytopenia but not with fibrinogen levels in children with meningococcal disease. Intensive Care Medicine 31(S1): S39, 2005

Binder A, Endler G, Mannhalter C, Marculescu R, Müller W, Faber J, Finn A, Zenz W. Polymorphisms in the interleukin 1 gene cluster in children with systemic meningococcaemia. Intensive Care Medicine 31(S1): S38, 2005

2004

Binder A, Müller MR, Moritz M, Müller W, Walcher W, Häring D, Faber J, Finn A, Mannhalter C, Zenz W. 4G/4G Allele of the Plasminogen Activator Inhibitor-1 gene associates with outcome in children with meningococcal disease. Monatsschrift Kinderheilkunde, 152 (suppl. 1), 2004

Müller MR, Binder A, Geishofer G, Zenz W, Müller W. Children with systemic meningococcal infection - a multicenter study. Monatsschrift Kinderheilkunde, 152 (suppl. 1), 2004

Munroe PB, Binder A, Garcia E, Wallace C, Kazeem G, Ben-Shlomo Y, Sweetnam P, Caulfield M, Skrabal F, Kotanko P. Haplotypes of the beta-2 adrenergic receptor associate with blood pressure levels in the Caerphilly Prospective Heart Study. J of Hum Hypertension, 18:S11, 2004

Binder A, Geishofer G, Trop M, Zöhrer B, Zenz W. Correlation of extension of purpura fulminans with the outcome of systemic meningococcal disease. Hämostaseologie, 24:A82, 2004

before 2004

Gratze G, Fortin J, Labugger R, Binder A, Kotanko P, Timmermann B, Luft FC, Höhe M, Skrabal F. b2 Adrenergic receptor variants affect resting blood pressure and agonist-induced vasodilation in young adult Caucasians. Hypertension, 33:1425-1430, 1999    [PDF]

Gratze G, Fortin J, Labugger R, Binder A, Schöner T, Kotanko P, Busjahn A, Höhe M, Luft FC, Skrabal F. Reduced b2-mediated whole body vasodilation in subjects with the Gly16-allele of the b2-adrenoceptor gene. J of Hypertension, 16(S2):422, 1998

Kotanko P, Binder A, Tasker J, DeFreitas P, Kamdar S, Clark AJL, Skrabal F, Caulfield M. Essential hypertension in African Caribbeans is associated with the Gly 16 allele of the b2 adrenoceptor. Ethnicity and Disease, 7 (suppl. 1):S6, 1997

Kotanko P, Binder A, Tasker J, DeFreitas P, Kamdar S, Clark AJL, Skrabal F, Caulfield M. Essential hypertension in African Caribbeans associates with a variant of the b2 adrenoceptor. Hypertension, 30(4):773-776, 1997    (Abstract) [Link to online version]

Rahman SU, Quing F, Rhodes CG, Kotanko P, Binder A, Ind PW, Jones T, Hughes JMB. Quantification of pulmonary b-adrenergic receptor (b-AR) downregulation in vivo with PET and correlation with functional tachyphylaxis and b-AR genotypes. Eur Resp J, 9(suppl.23): 271s, 1996

Kotanko P, Binder A, Skrabal F. Alleles of the human b2 adrenoceptor and their relationship to salt sensitivity. 7th European Meeting on Hypertension, Milan, 9th-12th June 1995, Book of abstracts, p97

Kotanko P, Höglinger O, Binder A, Skrabal F. Further evidence for reduced b2 adrenoceptor expression and modification of its density at a level beyond gene expression. Diabetologia, 38(1):126-128, 1995

Reimann-Weber A, Horwath J, Höglinger O, Binder A, Kotanko P, Kenner T, Skrabal F. Charakterisierung von Allelen des humanen b2 Adrenozeptors. Nieren- und Hochdruckkrankheiten, 23:S246-249, 1994

----------
Last modified: 11-Nov-2014